Her work consists primarily of works on paper and has been widely exhibited. She received her B.A. from Brown University and her M.F A. from SUNY Albany. Her work has been shown in the 2010 Whitney Biennial, and in many international museums and institutions including the Venice Biennale, Kunsthalle Wien (Austria), MassMoCA, Aldrich Museum, Weatherspoon Art Museum, Tang Museum, and SAFN Museum, Reykjavik, Iceland. Solo shows include Pierogi Gallery (Brooklyn, NY); Acme Gallery (Los Angeles, CA); Hales Gallery (London, England); and the Middlebury College Museum of Art (Middlebury, VT).

In 2013 she received a Civitella Ranieri Fellowship; in 2012 a Guggenheim Fellowship; in 2005 a fellowship in the category of Printmaking/Drawing/Artists' Books from the New York Foundation for the Arts; in 1993 grants from the Bohen Foundation and Arts Matters (Rockefeller Foundation). She has had artist residencies at Civitella Ranieri (Umbertide, Italy); Sint Trudo Abdij (Maele, Belgium); Middlebury College (Middlebury, VT); The Taft School (Watertown, CT); and Farpath Residency (Dijon, France).

In recent years Ms. Clements has taught at Rhode Island School of Design (Providence, RI), Maryland Institute College of Art (Baltimore, MD), California Institute of the Arts (Valencia, CA), Brooklyn College (Brooklyn, NY) and Princeton University (Princeton, NJ).

Her artwork is included in collections of the Museum of Modern Art (NY, NY); Whitney Museum of American Art (MY, NY); Saatchi Collection (London); Brown University (Providence, RI); Tang Museum (Saratoga Springs, NY), Princeton University Art Museum (Princeton, NJ); Henry Art Gallery (Seattle, WA) and other public and private collections.